What medication should NOT be administered for a suspected Calcium Channel Blocker overdose?

In cases of suspected calcium channel blocker (CCB) overdose, the administration of sodium bicarbonate is generally not recommended. Calcium channel blockers work by inhibiting calcium entry into cells, primarily affecting the cardiac and vascular smooth muscle, leading to depression of myocardial contractility and vasodilation. The standard treatment for CCB overdose often involves the use of calcium administration or supportive measures to counteract the effects of the overdose.

Calcium is conventionally administered to help restore cardiac function since it directly counteracts the effects of the CCB. Atropine can be used to manage bradycardia that may occur due to the overdose, while glucagon may be effective due to its positive inotropic effects and ability to help in countering the cardiovascular effects of CCBs.

Sodium bicarbonate is usually not beneficial in treating a CCB overdose because it primarily functions by buffering acidosis and does not address the underlying mechanism of calcium channel blockade. Administering sodium bicarbonate could lead to unnecessary complications and may not improve outcomes, making it inappropriate in this specific scenario.